S4 (Andarine) or Acetamidoxolutamide, is a SARM (Selective Androgen Receptor Modulator). Developed as drug to reduce muscle wasting - SARMs are a versatile compound that can help gain strength, muscle and lose fat. Andarine’s exceptional ability to help oxidize fat and keep the body from going catabolic while on a low calorie diet is its specialty. It will provide a hard, dry, lean look and increase vascularity. It provides notable strength and endurance even while in caloric deficit, and, at higher doses, it can even add hard muscle to your frame.
MK677 (Ibutamoren) acts as a potent, orally active growth hormone secretagogue, mimicking the GH stimulating action of the endogenous hormone ghrelin. It has been demonstrated to increase the release of, and produces sustained increases in plasma levels of several hormones including growth hormone and IGF-1, but without affecting cortisol levels. It is currently under development as a potential treatment for reduced levels of these hormones, such as in growth hormone deficient children or elderly adults, and human studies have shown it to increase both muscle mass and bone mineral density, making it a promising therapy for the treatment of frailty in the elderly. It also alters metabolism of body fat and so may have application in the treatment of obesity.
LGD4033 (Ligandrol) is an oral selective androgen receptor modulator, binds to the androgen receptor with high affinity and selectivity. It demonstrates anabolic activity in muscles, anti-resorptive and anabolic activity in bones and a robust selectivity for muscle and bone versus prostate and sebaceous glands. Results have shown increases in lean body mass and decreases in body fat. There is also a significant increase in strength, well being, as well as healing possibilities. LGD has shown the most ability of any SARM to put on size that could be considered a bulk.
RAD140 (Testolone) is a highly effective SARM (Selective Androgen Receptor Modulator) currently being studied for both anabolic and neuroprotective effects. It is in a class of androgen receptor (AR) ligands that are tissue selective, developed to treat muscle wasting associated with cancer, acute and chronic illness and age-related muscle loss. Recent research of RAD140 shows superior lean tissue selectivity, and reduced androgenic effects when compared to competing SARM compounds. This compound is being studied for neuroprotection as well; an important neural action of endogenous androgens that is relevant to neural health and resilience to neurodegenerative diseases, and to be as effective as testosterone in reducing cell death induced by apoptotic insults. RAD140 to be extremely effective at increasing athletic endurance, stamina, and speed, as well as strength and muscle volume in a short time frame. Because the product is anabolic in nature, it secondarily functions as a strong anti-catabolic, and will help preserve muscle mass during a caloric deficit / cutting cycle.
GW501516 (Cardarine) acts as a PPAR-β modulator. GW 501516 activates AMP-activated protein kinase and stimulates glucose uptake in skeletal muscle tissue, and GW-501516 has been demonstrated to reverse metabolic abnormalities in obese users with pre-diabetic metabolic syndrome, most likely by stimulating fatty acid oxidation. GW1516 increases muscle gene expression, especially genes involved in preferential lipid utilization. This shift changes the body’s metabolism to favor burning fat for energy instead of carbohydrates or muscle protein, potentially allowing fat loss effectively without experiencing muscle catabolism or the effects and satiety issues associated with low blood sugar. GW1516 significantly increases endurance which improved glucose tolerance and reduced fat mass accumulation even in a very high fat diet, suggesting that GW1516 may have a protective effect against obesity.
SR-9009,Stenabolic, works by stimulating the Rev-Erb protein which has an effect on circadian rhythms, fat-storing cells as well as glucose and lipid metabolism. By activating Rev-erb protein it increases cell production through mitochondria giving the muscle increased energy as well as giving the metabolism enhanced speed. Thus increasing the mitochondria in the muscle will result in strength gain as well as drastic energy increase to go along with strides in endurance. Using SR has been known to show up to 50% increases in complete all around endurance due to increases in mitochondria count. The biggest component that Stenabolic has is that it boosts metabolic activity and is known to mimic aerobic exercise without having to actually exercise hence being called “exercise in a bottle”. Research shows SR9009 uses body fat that is stored and uses it as energy for exercise. Due to the many effects it has it is a lean muscle gainer and can aid in strength gains while also burning fat.
MK677 (Ostarine) is a SARM (selective androgen receptor module) created by GTx to avoid and treat muscle wasting. It can, later on, be a cure for avoiding atrophy (total wasting away of a body part), cachexia, sarcopenia and Hormone or Testosterone Replacement Therapy. Ostarine binds to your muscles androgen receptors and causes significant muscle growth without the side effects seen in most performance enhancers. These gains are absolutely “keepable” and maintainable after use is discontinued, as long as workouts stay consistent and diet remains on track. Ostarine helps nutrient partitioning to a high degree. This effect has helped many achieve the supposed “impossible” feat of losing fat while gaining muscle at the same time. The versatility and safety of Ostarine make it a godsend in the magical world of SARMs.
YK11 is a myostatin inhibiting SARM that yields zero aromatization and zero side effects in test subjects. YK11 is an extreme Myostatin inhibitor that will accelerate muscle growth and unleash your test subject's potential. YK11 allows the test subject to stay in balance to produce the best and cleanest results possible! Our research suggests YK11 has a half life of about 6 hours, though it appears closer to 10 hours based upon plasma levels maintained in our test subjects.